Making a difference

Here you can read about some of the patients who suffer from diseases that are targeted by CBRI researchers. The nine profiled individuals have bravely struggled with illnesses such as Wiskott-Aldrich Syndrome, AIDS, lupus, cancer, and Crohn’s disease. They are the people who live in our neighborhoods. They are our friends, our co-workers, and our cherished family members. They are the reason that CBRI does research.

The quality of their lives — and the millions of others lives they stand in for — will improve in the next generation due to discoveries being made in CBRI laboratories by committed scientists who care to make a difference.


A New Life on the Ashes of the Old

Fernando Velazquez’s story

There’s something in the way he holds the basketball, with casual care, as if it were an old companion.


Caring Across Generations

Brave William’s story

Beverly Hough’s son, William, is like most three-year-old boys. He loves watching the polar bears eat breakfast at the zoo, finds walking a wobbly adventure, and fusses at naptime.

Grateful for Each New Day

Brenda Bellizeare’s story

Brenda Bellizeare works on the first floor of an old brownstone in Boston’s South End.


Hope and Chutzpah

Jane Brown’s story

“I want to see a cure for this in my lifetime,” Jane Brown says about Crohn’s disease, the painful inflammatory bowel disease that has turned her life upside down.


Immune Deficiency, Surplus of Caring

Steven Brandt’s story

When he was only two days old, Jan Brandt rushed her son Steven from a hospital in New Hampshire to Children’s Hospital in Boston.


Strength in Family

Amy Harned’s story

“Land is forgiving,” says Amy Harned, a devoted gardener. “If you plant something in one place and it doesn’t grow, you can move it to another place and give it a second chance.”


Testing the Limits

Darryl Sterling’s story

In his long battle with lupus, Darryl Sterling never doubted that he would lead a productive and fascinating life.

The Music Prevails

Chris Croteau’s story

Christopher Croteau, age 20, talks about the band Red Hot Chili Peppers and their outrageous bass guitarist, a man called Flea.


The Quiet Revolution

Jessica Keener’s story

Back in the late 1970s, when I first learned I had a fatal bone marrow disease called aplastic anemia, I had no idea that CBRI would play an essential role in my cure.

Vicki and Fred Modell

Tireless Advocacy, Boundless Spirit

Vicki and Fred Modell first encountered CBRI in the 1980s when their son Jeffrey was ill with a primary immune deficiency. One of the boy’s doctors was Fred S. Rosen, M.D., former president of the Institute. Since that time, Vicki and Fred have become steadfast supporters of CBRI.