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The Wagner Lab

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Publications

You are viewing recent publications from 1996 to the present day. You can also view all publications (1978-present).

A select list of our key papers is also available.

  1. Lu F, Chauhan AK, Fernandes SM, Walsh MT, Wagner DD, and Davis III AE. The effect of C1 inhibitor on intestinal ischemia and reperfusion injury. Am J Physiol Gastrointest Liver Physiol 295: G1042-1049, 2008.
  2. Kisucka J, Chauhan AK, Patten IS, Yesilaltay A, Neumann C, Van Etten RA, Krieger M, Wagner DD. Peroxiredoxin1 prevents excessive endothelial activation and early atherosclerosis. Circ Res. 103: 598-605, 2008.
  3. Ho-Tin-Noe B, Goerge T, Cifuni SM, Duerschmied D, and Wagner DD. Platelet granule secretion continuously prevents intra-tumor hemorrhage. Cancer Res 68: 6851-6858, 2008.
  4. Noubade R, del Rio R, McElvany B, Zachary JF, Millward JM, Wagner DD, Offner H, Blankenhorn EP and Teuscher C. von Willebrand Factor influences blood brain barrier permeability and brain inflammation in experimental allergic encephalomyelitis. Am J Path 173:892-900, 2008.
  5. Cifuni SM, Wagner DD and Bergmeier W. CalDAG-GEFI and protein kinase C (PKC) represent alternative pathways leading to activation of integrin αIIbβ3 in platelets. Blood 112: 1696-703, 2008.
  6. Chauhan AK, Kisucka J, Brill A, Walsh MT, Scheiflinger F and Wagner DD. ADAMTS13 - A new link between thrombosis and inflammation. J Exp Med 205: 2065-2074, 2008.
  7. Dole VS, Matuskova J, Vasile E, Yesilaltay A, Bergmeier W, Bernimoulin M, Wagner DD and Krieger M. Thrombocytopenia and platelet abnormalities in high density lipoprotein receptor deficient mice. Arterioscler Thromb Vasc Biol 28: 1111-1116, 2008.
  8. Wagner DD and Frenette PS. The vessel wall and its interactions. Blood 111: 5271-5281, 2008.
  9. Goerge T, Ho-Tin-Noe B, Carbo C, Benarafa C, Remold-O’Donnell E, Zhao BQ, Cifuni SM and Wagner DD. Inflammation induces hemorrhage in thrombocytopenia. Blood 111: 4958-4964, 2008.
  10. Chauhan AK, Walsh MT, Zhu G, Ginsburg D, Wagner DD and Motto DG. The combined roles of ADAMTS13 and VWF in murine models of TTP, endotoxemia, and thrombosis. Blood 111: 3452-3457, 2008.
  11. Bergmeier W, Chauhan AK and Wagner DD. Glycoprotein Ibα and von Willebrand factor in primary platelet adhesion and thrombus formation: Lessons from mutant mice. Thromb Haemost 99: 264-270, 2008.
  12. Chauhan AK, Kisucka J, Cozzi MR, Walsh MT, Moretti FA, Battiston M, Mazzucato M, De Marco L, Baralle FE, Wagner DD and Muro AF. Prothrombotic effects of fibronectin isoforms containing the EDA domain. Arterioscler Thromb Vasc Biol 28: 296-301, 2008.
  13. Frederix K, Chauhan AK, Kisucka J, Zhao BQ, Hoff EI, Spronk HMH, ten Cate H and Wagner DD. Platelet adhesion receptors do not modulate infract volume after a photochemically induced stroke in mice. Brain Res 1185: 239-245, 2007.
  14. Junt T, Schulze H, Chen Z, Massberg S, Goerge T, Krueger A, Wagner DD, Graf T, Italiano JE Jr, Shivdasani RA and von Andrian UH. Dynamic visualization of thrombopoiesis within bone marrow. Science 317: 1767-1770, 2007.
  15. Dole VS, Bergmeier W, Patten IS, Hirahashi J, Mayadas TN and Wagner DD. PSGL-1 regulates platelet P-selectin-mediated endothelial activation and shedding of P-selectin from activated platelets. Thromb Haemost 98: 806-812, 2007.
  16. Bergmeier W, Goerge T, Wang HW, Crittenden JR, Baldwin ACW, Cifuni SM, Housman DE, Graybiel AM, and Wagner DD. Mice lacking the signaling molecule, CalDAG-GEFI, represent a model for leukocyte adhesion deficiency type III. In Press, J Clin Invest. [Abstract]
  17. Hafezi-Moghadam A, Thomas KL, and Wagner DD. ApoE-deficiency leads to a progressive age-dependent blood brain barrier leakage. Am J Physiol Cell Physiol 292: C1256-1262, 2007. [Abstract]
  18. Denis CV and Wagner DD. Platelet adhesion receptors and their ligands in mouse models of thrombosis. Arterioscler Thromb Vasc Biol 27: 728-739, 2007. [Abstract]
  19. Chauhan AK, Kisucka J, Lamb CB, Bergmeier W, Wagner DD. von Willebrand Factor and Factor VIII are independently required to form stable occlusive thrombi in injured veins. Blood 109: 2424-2429, 2007. [Abstract]
  20. Chauhan AK, Goerge T, Schneider SW and Wagner DD. Formation of platelet strings and microthrombi in the presence of ADAMTS-13 inhibitor does not require P-selectin or β3 integrin. J Thromb Haemost 5: 583-589, 2007. [Abstract]
  21. Babic AM, Josefsson EC, Bergmeier W, Wagner DD, Kaufman RM, Silberstein LE, Stossel TP, Hartwig JH and Hoffmeister KM. In vitro function and phagocytosis of galactosylated platelet concentrates following long-term refrigeration. Transfusion 47: 442-451, 2007. [Abstract]
  22. Zhu L, Bergmeier W, Wu J, Jiang H, Stalker TJ, Cieslak M, Fan R, Boumsell L, Kumanogoh A, Kikutani H, Tamagnone L, Wagner DD, Milla ME and Brass LF. Regulated surface expression and shedding support a dual role for semaphorin 4D in platelet responses to vascular injury. Proc Natl Acad Sci USA 104: 1621-1626, 2007. [Abstract]
  23. Bergmeier W and Wagner DD. Inflammation. In: Platelets. 2nd Edition. Michelson A (Ed.) San Diego: Elsevier — Academic Press, 2006.
  24. Bergmeier W, Piffath CL, Goerge T, Cifuni SM. Ruggeri ZM, Ware J and Wagner DD. The role of platelet adhesion receptor GPIbα far exceeds that of its main ligand von Willebrand factor in arterial thrombosis. Proc Natl Acad Sci. 103: 16900-16905, 2006. [Abstract]
  25. Yang H, Reheman A, Chen P, Hynes RO, Freedman J, Wagner DD and Ni H. Fibrinogen and von Willebrand Factor-independent platelet aggregation in vitro and in vivo. J Thromb Haemost 4: 2230-2237, 2006. [Abstract]
  26. Hirahashi J, Mekala D, Van Ziffle J, Xiao L, Saffaripour S, Wagner DD, Shapiro SD, Lowell C and Mayadas TN. Mac-1 signaling via Src-family and Syk kinases results in elastase-dependent thrombohemorrhagic vasculopathy. Immunity 25: 271-283, 2006. [Abstract]
  27. Yang D, Zhang Y, Nguyen HG, Koupenova M, Chauhan AK, Makitalo M, Jones MR, St. Hilaire C, Seldin DC, Toselli P, Lamperti E, Schreiber BM, Gavras H, Wagner DD and Ravid K. The adenosine 2B receptor protects against inflammation and excessive vascular adhesion. J Clin Invest 116:1912-1923, 2006. [Abstract]
  28. Matuskova J, Chauhan AK, Cambien B, Astrof S, Dole VS, Piffath CL, Hynes RO and Wagner DD. Decreased plasma fibronectin leads to delayed thrombus growth in injured arterioles. Arterioscler Thromb Vasc Biol 26:1391-1396, 2006. [Abstract]
  29. Chauhan AK, Motto DG, Lamb CB, Bergmeier W, Dockal M, Plaimauer B, Scheiflinger F, Ginsburg D and Wagner DD. Systemic anti-thrombotic effects of ADAMTS13. J Exp Med 203:767-776, 2006. [Abstract]
  30. Kisucka J, Butterfield CE, Duda DG, Eichenberger SC, Saffaripour S, Ware J, Ruggeri ZM, Jain RK, Folkman J and Wagner DD. Platelets and platelet adhesion support angiogenesis while preventing excessive hemorrhage. Proc Natl Acad Sci USA 103: 855-860, 2006. [Abstract]
  31. Kamath AF, Chauhan AK, Kisucka J, Dole VS, Loscalzo J, Handy DE and Wagner DD. Elevated levels of homocysteine compromise blood-brain barrier integrity in mice. Blood 107: 591-593, 2006. [Abstract]
  32. Aktas B, Pozgajova M, Bergmeier W, Sunnarborg SW, Offermanns S, Lee DC, Wagner DD, Nieswandt B. Aspirin induces platelet receptor shedding via ADAM17 (TACE). J Biol Chem 280: 39716-39722, 2005. [Abstract]
  33. Motto DG, Chauhan AK, Zhu G, Homeister J, Lamb CB, Desch KC, Zhang W, Tsai HM, Wagner DD, and Ginsburg D. Shigatoxin triggers thrombotic thrombocytopenic purpura in genetically susceptible ADAMTS13-deficient mice. J Clin Invest 115: 2752-2761, 2005 [Abstract]
  34. Dole VS, Bergmeier W, Mitchell HA, Eichenberger SC and Wagner DD. Activated platelets induce Weibel-Palade body secretion and leukocyte rolling in vivo: Role of P-selectin. Blood 106: 2334-2339, 2005. [Abstract]
  35. Polgar J, Matuskova J and Wagner DD. The P-selectin, tissue factor, coagulation triad. J Thromb Haemost 8: 1590-1596, 2005. [Abstract]
  36. Wagner DD. New links between inflammation and thrombosis. Arterioscler Thromb Vasc Biol 25: 1321-1324, 2005. [Abstract]
  37. Wang, HW, Babic, AM, Mitchell HA, Liu K and Wagner DD. Elevated soluble ICAM-1 levels induce immune deficiency and increase adiposity in mice. FASEB J 19: 1018-1020, 2005. [Abstract]
  38. Cai S, Dole VS, Bergmeier W, Scafidi J, Feng H, Wagner DD and Davis AE III. Direct role for C1 inhibitor in regulation of leukocyte adhesion. J Immunol 174: 6462-6466, 2005. [Abstract]
  39. Babic AM, Wang HW, Lai MJ, Daniels TG, Felbinger TW, Burger PC, Stricker-Krongrad A and Wagner DD. ICAM-1 and β2 integrin deficiency impairs fat oxidation and insulin metabolism during fasting. Mol Med 10: 72-79, 2004. [Abstract]
  40. Ginsburg D and Wagner DD. Structure, biology and genetics of von Willebrand factor. In: Hematology: Basic Principles and Practices. 4th Edition. Hoffman R, Benz EJ, Shattil SJ, Furie B, Cohen HJ, Silberstein LE and McGlave P. (Eds.). New York: Churchill Livingstone, 2004.
  41. Bergmeier W, Piffath CL, Cheng G, Dole VS, Zhang Y, von Andrian UH, Wagner DD. Tumor necrosis factor-alpha-converting enzyme (ADAM17) mediates GPIbalpha shedding from platelets in vitro and in vivo. Circ Res 95: 677-683, 2004. [Abstract]
  42. Crittenden JR, Bergmeier W, Zhang Y, Piffath CL, Liang Y, Wagner DD, Housman DE, Graybiel AM. CalDAG-GEFI integrates signaling for platelet aggregation and thrombus formation. Nat Med 10: 982-986, 2004. [Abstract]
  43. Kondo T, Hafezi-Moghadam A, Thomas K, Wagner DD and Kahn CR. Mice lacking insulin or insulin-like growth factor 1 receptors in vascular endothelial cells maintain normal blood-brain barrier. Biochem Biophys Res Commun 317: 315-320, 2004. [Abstract]
  44. Bergmeier W, Rabie T, Strehl A, Piffath CL, Prostredna M, Wagner DD and Nieswandt B. GPVI down-regulation in murine platelets through metalloproteinase-dependent shedding. Thromb Haemost 91: 951-958. 2004. [Abstract]
  45. Cambien B and Wagner DD. A new role in hemostasis for the adhesion receptor P-selectin. Trends Mol Med 10: 179-186, 2004. [Abstract]
  46. Wagner DD and Burger PC. Platelets in inflammation and thrombosis. Arterioscler Thromb Vasc Biol 23: 2131-2137, 2003. [Abstract]
  47. Wagner DD. Shear madness in TNF- signaling. Blood 102:2711-2712, 2003.
  48. Matsushita K, Morrell CN, Cambien B, Yang SX, Yamakuchi M, Bao C, Hara M, Quick RA, Cao W, OíRourke B, Lowenstein JM, Pevsner J, Wagner DD and Lowenstein CJ. Nitric oxide regulates exocytosis by S-nitrosylation of N-ethylmaleimide-sensitive factor. Cell 115:139-150, 2003. [Abstract]
  49. Cambien B, Bergmeier W, Saffaripour S, Mitchell HA and Wagner DD. Anti-thrombotic activity of Tumor Necrosis Factor-α. J Clin Invest. 112:1589-1596, 2003. [Abstract]
  50. Wagner DD, Burger PC. Platelets in Inflammation and Thrombosis. ATVB Conference Plenary Lecture. Arterioscler Thromb Vasc Biol. 23:2131-2137, 2003. [Abstract]
  51. Myers DD, Hawley AE, Farris DM, Wrobelski SK, Tanaporn P, Schaub RG, Wagner DD, Kumar A and Wakefield TW. P-selectin and leukocyte microparticles are associated with venous thrombogenesis. J Vasc Surg. 38:1075-1089, 2003. [Abstract]
  52. Bergmeier W, Burger PC, Piffath CL, Hoffmeister KM, Hartwig JH, Nieswandt B, Wagner DD. Metalloproteinase inhibitors improve the recovery and hemostatic function of in vitro aged or injured mouse platelets. Blood. 102:4229-4235, 2003. [Abstract]
  53. Ni H, Papalia JM, Degen JL, Wagner DD. Control of thrombus embolization and fibronectin internalization by integrin αIIbβ3 engagement of the fibrinogen γ chain. Blood. 102:3609-3614, 2003. [Abstract]
  54. Hrachovinova I , Cambien B, Hafezi-Moghadam A, Kappelmayer J, Camphausen RT, Widom A, Xia L, Kazazian HH, Schaub RG, McEver RP, Wagner DD. Interaction of P-selectin and PSGL-1 generates microparticles that correct hemostasis in a mouse model of hemophilia A. Nat Med. 9: 1020-1025, 2003 [Abstract]
  55. Italiano JE Jr, Bergmeier W, Tiwari S, Falet H, Hartwig JH, Hoffmeister KM, Andre P, Wagner DD, Shivdasani RA. Mechanisms and implications of platelet discoid shape. Blood. 101:4789-4796, 2003. [Abstract]
  56. Burger PC and Wagner DD. Platelet P-selectin facilitates atherosclerotic lesion development. Blood. 101:2661-2666. 2003. [Abstract]
  57. Ni H, Yuen PST, Papalia JM, Trevithick JE, Sakai T, Fassler R, Hynes RO and Wagner DD. Plasma fibronectin promotes thrombus growth and stability in injured arterioles. Proc Natl Acad Sci USA 100: 2415-2419, 2003. [Abstract]
  58. Hoffmeister KM, Felbinger TW, Falet H, Denis CV, Bergmeier W, Mayadas TN, von Andrian UH, Wagner DD, Stossel TP and Hartwig JH. The clearance mechanism of chilled blood platelets. Cell. 112: 87-97, 2003 [Abstract]
  59. Sethi S, Ziouzenkova O, Ni H, Wagner DD, Plutzky J and Mayadas TN. Oxidized omega-3 fatty acids in fish oil inhibit leukocyte-endothelial interactions through activation of PPAR α. Blood. 100: 1340-1346, 2002. [Abstract]
  60. Götte M, Joussen AM, Klein C, André P, Wagner DD, Hinkes MT, Kirchhof B, Adamis AP and Bernfield M. Role of syndecan-1 in leukocyte-endothelial interactions in the ocular vasculature. Invest Ophthalmol Vis Sci 43: 1135-1141, 2002. [Abstract]
  61. André P, Prasad KSS, Denis CV, He M, Papalia JM, Hynes RO, Phillips DR and Wagner DD. CD40L stabilizes arterial thrombi by a β3 integrin-dependent mechanism. Nature Med. 8: 247-252, 2002.[Abstract]
  62. Methia, N, André P, Hafezi-Moghadam, A, Economopoulos, M, Thomas, KL and Wagner, DD. ApoE deficiency compromises the blood brain barrier especially after injury. Mol Med. 7: 810-815, 2001 [Abstract]
  63. Denis, CV, Andre, P, Saffaripour, S, Wagner, DD. Defect in regulated secretion of P-selectin affects leukocyte recruitment in von Willebrand factor-deficient mice. Proc Natl Acad Sci U S A. 98:4072-4077, 2001 [Abstract]
  64. Denis, CV, Kwack, K, Saffaripour, S, Maganti, S, Andre, P, Schaub, RG, Wagner, DD. Interleukin 11 significantly increases plasma von Willebrand factor and factor VIII in wild type and von Willebrand disease mouse models. Blood. 97:465-472, 2001 [Abstract]
  65. Methia, N, Andre, P, Denis, CV, Economopoulos, M, Wagner, DD. Localized reduction of atherosclerosis in von Willebrand factor- deficient mice. Blood. 98:1424-1428, 2001 [Abstract]
  66. Ni, H, Ramakrishnan, V, Ruggeri, ZM, Papalia, JM, Phillips, DR, Wagner, DD. Increased thrombogenesis and embolus formation in mice lacking glycoprotein V. Blood. 98:368-373, 2001 [Abstract]
  67. Niederman, R, Westernoff, T, Lee, C, Mark, LL, Kawashima, N, Ullman-Culler, M, Dewhirst, FE, Paster, BJ, Wagner, DD, Mayadas, T, Hynes, RO, Stashenko, P. Infection-mediated early-onset periodontal disease in P/E-selectin- deficient mice. J Clin Periodontol. 28:569-575, 2001 [Abstract]
  68. Andre, P, Denis, CV, Ware, J, Saffaripour, S, Hynes, RO, Ruggeri, ZM, Wagner, DD. Platelets adhere to and translocate on von Willebrand factor presented by endothelium in stimulated veins. Blood. 96:3322-3328, 2000 [Abstract]
  69. Andre, P, Hartwell, D, Hrachovinova, I, Saffaripour, S, Wagner, DD. Pro-coagulant state resulting from high levels of soluble P-selectin in blood. Proc Natl Acad Sci U S A. 97:13835-13840, 2000 [Abstract]
  70. Dong, ZM, Brown, AA, Wagner, DD. Prominent role of P-selectin in the development of advanced atherosclerosis in ApoE-deficient mice. Circulation. 101:2290-2295, 2000 [Abstract]
  71. Frenette, PS, Denis, CV, Weiss, L, Jurk, K, Subbarao, S, Kehrel, B, Hartwig, JH, Vestweber, D, Wagner, DD. P-Selectin glycoprotein ligand 1 (PSGL-1) is expressed on platelets and can mediate platelet-endothelial interactions in vivo. J Exp Med. 191:1413-1422, 2000 [Abstract]
  72. Ni, H, Denis, CV, Subbarao, S, Degen, JL, Sato, TN, Hynes, RO, Wagner, DD. Persistence of platelet thrombus formation in arterioles of mice lacking both von Willebrand factor and fibrinogen. J Clin Invest. 106:385-392, 2000 [Abstract]
  73. Denis, CV, Wagner, DD. Insights from von Willebrand disease animal models. Cell Mol Life Sci. 56:977-990, 1999 [Abstract]
  74. Enjyoji, K, Sevigny, J, Lin, Y, Frenette, PS, Christie, PD, Esch, JS, 2nd, Imai, M, Edelberg, JM, Rayburn, H, Lech, M, Beeler, DL, Csizmadia, E, Wagner, DD, Robson, SC, Rosenberg, RD. Targeted disruption of cd39/ATP diphosphohydrolase results in disordered hemostasis and thromboregulation. Nat Med. 5:1010-1017, 1999 [Abstract]
  75. Ginsburg, D, Wagner, DD. Structure and biology of von Willebrand factor. In: Hoffman R, Benz EJ, Shattil SJ, Furie B, Cohen HJ, Silbertstein LE, McGlave P, eds. Hematology: Basic Principles and Practice. New York: Churchill Livingstone; 1999:1937-1945
  76. Hartwell, DW, Wagner, DD. New discoveries with mice mutant in endothelial and platelet selectins. Thromb Haemost. 82:850-857, 1999 [Abstract]
  77. Jia, GQ, Gonzalo, JA, Hidalgo, A, Wagner, D, Cybulsky, M, Gutierrez-Ramos, JC. Selective eosinophil transendothelial migration triggered by eotaxin via modulation of Mac-1/ICAM-1 and VLA-4/VCAM-1 interactions. Int Immunol. 11:1-10, 1999 [Abstract]
  78. Methia, N, Denis, CV, Wagner, DD. Carboxypeptidase E does not mediate von Willebrand factor targeting to storage granules. Eur J Cell Biol. 78:884-891, 1999 [Abstract]
  79. Robinson, SD, Frenette, PS, Rayburn, H, Cummiskey, M, Ullman-Cullere, M, Wagner, DD, Hynes, RO. Multiple, targeted deficiencies in selectins reveal a predominant role for P-selectin in leukocyte recruitment. Proc Natl Acad Sci U S A. 96:11452-11457, 1999 [Abstract]
  80. Shi, C, Feinberg, MW, Zhang, D, Patel, A, Sim, CU, Dong, ZM, Chapman, SM, Gutierrez-Ramos, JC, Wagner, DD, Sibinga, NE, Haber, E. Donor MHC and adhesion molecules in transplant arteriosclerosis. J Clin Invest. 103:469-474, 1999 [Abstract]
  81. Soriano, SG, Wang, YF, Wagner, DD, Frenette, PS. P- and E-selectin-deficient mice are susceptible to cerebral ischemia- reperfusion injury. Brain Res. 835:360-364, 1999 [Abstract]
  82. Berger, G, Hartwell, DW, Wagner, DD. P-Selectin and platelet clearance. Blood. 92:4446-4452, 1998 [Abstract]
  83. de Mora, F, Williams, CM, Frenette, PS, Wagner, DD, Hynes, RO, Galli, SJ. P- and E-selectins are required for the leukocyte recruitment, but not the tissue swelling, associated with IgE- and mast cell-dependent inflammation in mouse skin. Lab Invest. 78:497-505, 1998 [Abstract]
  84. Denis, C, Methia, N, Frenette, PS, Rayburn, H, Ullman-Cullere, M, Hynes, RO, Wagner, DD. A mouse model of severe von Willebrand disease: defects in hemostasis and thrombosis. Proc Natl Acad Sci U S A. 95:9524-9529, 1998 [Abstract]
  85. Dong, ZM, Chapman, SM, Brown, AA, Frenette, PS, Hynes, RO, Wagner, DD. The combined role of P- and E-selectins in atherosclerosis. J Clin Invest. 102:145-152, 1998 [Abstract]
  86. Dong, ZM, Wagner, DD. Leukocytes fighting against obesity. Mol Psychiatry. 3:8-9, 1998
  87. Dong, ZM, Wagner, DD. Leukocyte-endothelium adhesion molecules in atherosclerosis. J Lab Clin Med. 132:369-375, 1998 [Abstract]
  88. Fleming, JC, Berger, G, Guichard, J, Cramer, EM, Wagner, DD. The transmembrane domain enhances granular targeting of P-selectin. Eur J Cell Biol. 75:331-343, 1998 [Abstract]
  89. Frenette, PS, Moyna, C, Hartwell, DW, Lowe, JB, Hynes, RO, Wagner, DD. Platelet-endothelial interactions in inflamed mesenteric venules. Blood. 91:1318-1324, 1998 [Abstract]
  90. Frenette, PS, Subbarao, S, Mazo, IB, von Andrian, UH, Wagner, DD. Endothelial selectins and vascular cell adhesion molecule-1 promote hematopoietic progenitor homing to bone marrow. Proc Natl Acad Sci U S A. 95:14423-14428, 1998 [Abstract]
  91. Hartwell, DW, Butterfield, CE, Frenette, PS, Kenyon, BM, Hynes, RO, Folkman, J, Wagner, DD. Angiogenesis in P- and E-selectin-deficient mice. Microcirculation. 5:173-178, 1998 [Abstract]
  92. Hartwell, DW, Mayadas, TN, Berger, G, Frenette, PS, Rayburn, H, Hynes, RO, Wagner, DD. Role of P-selectin cytoplasmic domain in granular targeting in vivo and in early inflammatory responses. J Cell Biol. 143:1129-1141, 1998 [Abstract]
  93. Homeister, JW, Zhang, M, Frenette, PS, Hynes, RO, Wagner, DD, Lowe, JB, Marks, RM. Overlapping functions of E- and P-selectin in neutrophil recruitment during acute inflammation. Blood. 92:2345-2352, 1998 [Abstract]
  94. Mazo, IB, Gutierrez-Ramos, JC, Frenette, PS, Hynes, RO, Wagner, DD, von Andrian, UH. Hematopoietic progenitor cell rolling in bone marrow microvessels: parallel contributions by endothelial selectins and vascular cell adhesion molecule 1. J Exp Med. 188:465-474, 1998 [Abstract]
  95. Seiler, KP, Ma, Y, Weis, JH, Frenette, PS, Hynes, RO, Wagner, DD, Weis, JJ. E and P selectins are not required for resistance to severe murine lyme arthritis. Infect Immun. 66:4557-4559, 1998. [Abstract]
  96. Dong, ZM, Gutierrez-Ramos, JC, Coxon, A, Mayadas, TN, Wagner, DD. A new class of obesity genes encodes leukocyte adhesion receptors. Proc Natl Acad Sci U S A. 94:7526-7530, 1997. [Abstract]
  97. Frenette, PS, Wagner, DD. Insights into selectin function from knockout mice. Thromb Haemost. 78:60-64, 1997. [Abstract]
  98. Hynes, RO, Wagner, DD. Genetic manipulation of vascular adhesion molecules in mice. J Clin Invest. 100:S11-13, 1997. [Abstract]
  99. Johnson, RC, Chapman, SM, Dong, ZM, Ordovas, JM, Mayadas, TN, Herz, J, Hynes, RO, Schaefer, EJ, Wagner, DD. Absence of P-selectin delays fatty streak formation in mice. J Clin Invest. 99:1037-1043, 1997. [Abstract]
  100. Subramaniam, M, Saffaripour, S, Van De Water, L, Frenette, PS, Mayadas, TN, Hynes, RO, Wagner, DD. Role of endothelial selectins in wound repair. Am J Pathol. 150:1701-1709, 1997. [Abstract]
  101. Walter, UM, Ayer, LM, Manning, AM, Frenette, PS, Wagner, DD, Hynes, RO, Wolitzky, BA, Issekutz, AC. Generation and characterization of a novel adhesion function blocking monoclonal antibody recognizing both rat and mouse E-selectin. Hybridoma. 16:355-361, 1997. [Abstract]
  102. Walter, UM, Ayer, LM, Wolitzky, BA, Wagner, DD, Hynes, RO, Manning, AM, Issekutz, AC. Characterization of a novel adhesion function blocking monoclonal antibody to rat/mouse P-selectin generated in the P-selectin-deficient mouse. Hybridoma. 16:249-257, 1997. [Abstract]
  103. Weiser, MR, Pechet, TT, Williams, JP, Ma, M, Frenette, PS, Moore, FD, Kobzik, L, Hines, RO, Wagner, DD, Carroll, MC, Hechtman, HB. Experimental murine acid aspiration injury is mediated by neutrophils and the alternative complement pathway. J Appl Physiol. 83:1090-1095, 1997. [Abstract]
  104. Frenette, PS, Mayadas, TN, Rayburn, H, Hynes, RO, Wagner, DD. Susceptibility to infection and altered hematopoiesis in mice deficient in both P- and E-selectins. Cell. 84:563-574, 1996. [Abstract]
  105. Frenette, PS, Wagner, DD. Adhesion molecules--Part 1. N Engl J Med. 334:1526-1529, 1996.
  106. Frenette, PS, Wagner, DD. Adhesion molecules--Part II: Blood vessels and blood cells. N Engl J Med. 335:43-45, 1996.
  107. Hynes, RO, Wagner, DD. Genetic manipulation of vascular adhesion molecules in mice. J Clin Invest. 98:2193-2195, 1996.
  108. Mayadas, TN, Mendrick, DL, Brady, HR, Tang, T, Papayianni, A, Assmann, KJ, Wagner, DD, Hynes, RO, Cotran, RS. Acute passive anti-glomerular basement membrane nephritis in P-selectin- deficient mice. Kidney Int. 49:1342-1349, 1996. [Abstract]
  109. Pinsky, DJ, Naka, Y, Liao, H, Oz, MC, Wagner, DD, Mayadas, TN, Johnson, RC, Hynes, RO, Heath, M, Lawson, CA, Stern, DM. Hypoxia-induced exocytosis of endothelial cell Weibel-Palade bodies. A mechanism for rapid neutrophil recruitment after cardiac preservation. J Clin Invest. 97:493-500, 1996. [Abstract]
  110. Subramaniam, M, Frenette, PS, Saffaripour, S, Johnson, RC, Hynes, RO, Wagner, DD. Defects in hemostasis in P-selectin-deficient mice. Blood. 87:1238-1242, 1996. [Abstract]
  111. Tang, T, Frenette, PS, Hynes, RO, Wagner, DD, Mayadas, TN. Cytokine-induced meningitis is dramatically attenuated in mice deficient in endothelial selectins. J Clin Invest. 97:2485-2490, 1996. [Abstract]

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