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Timothy A. Springer |
Springer Career Narrative |
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Latham Family Professor of Pathology
Department of Pathology, Harvard Medical School
The CBR Institute for Biomedical Research, Inc.
The CBR Institute for Biomedical Research, Inc.
200 Longwood Avenue
Room 251
Boston, MA 02115
Phone: (617) 278-3200
Fax: (617) 278-3232
e-mail: springer@cbr.med.harvard.edu |
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Major Research Interests:
Adhesion Receptors of the Immune System |
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Education:
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| 1971 |
B.A. |
University of California, Berkeley (Biochemistry) |
| 1976 |
Ph.D. |
Harvard University (Biochemistry and Molecular Biology) |
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Postdoctoral Training: |
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| 1976-1977 |
National Institutes of Health Research Fellow, University of Cambridge,England, and MRC Laboratory of Molecular Biology, Cambridge, England (César Milstein)
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Academic Appointments:
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| 1977-1983 |
Assistant Professor |
Harvard Medical School |
| 1983-1989 |
Associate Professor |
Harvard Medical School |
| 1981-1988 |
Chief |
Laboratory of Membrane Immunochemistry, Dana Farber Cancer Institute |
| 1988-1992 |
Vice President |
Center for Blood Research |
| 1989- |
Latham Family Professor of Pathology |
Harvard Medical School |
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Awards and Honors: |
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| 1966 |
National Merit Scholar |
| 1971 |
Phi Beta Kappa |
| 1971 |
Biochemistry Departmental Citation (awarded to most outstanding graduate) |
| 1971 |
B.A. with Distinction in General Scholarship and Great Distinction in the Major |
| 1981 |
American Cancer Society Junior Faculty Research Award |
| 1984 |
American Cancer Society Faculty Research Award |
| 1988 |
MERIT Grant Award, National Institutes of Health |
| 1989- |
Councilor, International Leukocyte Workshop |
| 1992 |
Distinguished Lectureship, Vanderbilt School of Medicine |
| 1993 |
American Heart Association Basic Research Prize |
| 1994 |
Royal Society of Medicine, Medal, Visiting Professor, United Kingdom |
| 1995 |
William B. Coley Medal for Distinguished Research in Fundamental Immunology, Cancer Research Institute |
| 1995 |
Marie T. Bonazinga Award for Excellence in Leukocyte Biology Research, Society for Leukocyte Biology |
| 1996- |
Member, National Academy of Sciences |
| 1997 |
Wellcome Visiting Professor, Wayne State University |
| 2001- |
Fellow, American Academy of Arts and Sciences |
| 2004 |
MERIT Grant Award, National Institutes of Health |
| 2004 |
Crafoord Prize in Polyarthritis, Royal Swedish Academy of Sciences |
| 2004 |
Fellowship, John Simon Guggenheim Memorial Foundation |
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Major Committee Assignments:
National and Regional: |
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| 1980 |
Panel Member, NIAID Study Group on Immunology |
| 1982 |
Ad Hoc Member, Experimental Immunology Study Section |
| 1985 |
Ad Hoc Member, Allergy and Immunology Study Section |
| 1986 |
Ad Hoc Member, Board of Scientific Councilors, National Institutes of Allergy and Infectious Disease |
| 1986-1990 |
Member, Allergy and Immunology Study Section, National Institutes of Health |
| 1989- |
Councilor, International Leukocyte Workshop |
| 1990 |
Organizer, International Conference on Leukocyte Adhesion Molecules, Titisee, Germany |
| 1990-1992 |
Executive Committee, International Congresses on Inflammation |
| 1991 |
Organizer, Banbury Center Conference on Adhesion Molecule Receptors and Disease, Cold Spring Harbor, New York |
| 1991 |
Organizer, Juan March Foundation Workshop on Adhesion Receptors in the Immune System, Madrid, Spain |
| 1991-1993 |
Scientific Advisory Board, New England Regional Primate Research Center |
| 1994 |
Co-Organizer, Keystone Symposium on "Biology of Physicochemical Interactions at the Cell Surface" |
| 1992-1994 |
Chair, Adhesion Structures Section, Fifth International Leukocyte Workshop |
| 1994-1996 |
Chair, Endothelial Cell Section, Sixth International Leukocyte Workshop |
| 1996-2000 |
Howard Hughes Medical Institute, Scientific Review Board |
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Harvard: |
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| 1982-1994 |
Committee on Cell and Developmental Biology |
| 1989- |
Executive Committee, Committee on Immunology |
| 1989-1991 |
Ryan Fellowship Committee |
| 1989-1992 |
Center for Blood Research, Planning Director for Space in the Warren Alpert Building |
| 1990-1993 |
Member and then Chair, Dunham Lectureship Committee |
| 1991-1993 |
Faculty Fellowships Committee |
| 1991- |
Chair and member, numerous ad hoc search committees for full professors and junior faculty members |
| 1991-1994 |
Committee on Immunology, Admissions Committee |
| 1989- |
Appointments Committee, Center for Blood Research |
| 1993-1994 |
Health Sciences and Technology Fellowships Committee |
| 1993- |
Executive Committee, Department of Pathology |
| 1994- |
Ph.D. Program Faculty in Biomedical and Biological Sciences |
| 1996- |
Member, Faculty Council |
| 2002- |
Overseer, Board of Overseers, The CBR Institute for Biomedical Research, Inc. |
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Editorial Boards:
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| 1981-1985 |
Associate Editor, Journal of Immunology |
| 1981- |
Editorial Board, Hybridoma |
| 1985-1995 |
Advisory Editor, Journal of Experimental Medicine |
| 1988- |
Editorial Board, Regional Immunology |
| 1988-1993 |
Editorial Board, Cellular Immunology |
| 1988-1992 |
Editorial Board, Journal of Clinical Immunology |
| 1989-1992 |
Editorial Board, New Biologist |
| 1989-1992 |
Editorial Board, Cell Regulation (Molecular Biology of the Cell) |
| 1992-1996 |
Associate Editor, Molecular Biology of the Cell |
| 1996-2001 |
Editorial Board, Immunological Reviews |
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Memberships and Committee Assignments in Professional Societies: |
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| 1979- |
American Association of Immunologists |
| 1981-1994 |
Reticuloendothelial Society |
| 1982- |
American Society of Biological Chemists |
| 1985-1986 |
American Association of Immunologists Meeting, Block Chairman, Macrophages & Natural Killer Cells |
| 1986 |
Reticuloendothelial Society, Membership Chair |
| 1987 |
Program Committee, Reticuloendothelial Society (chair 1989) |
| 1989- |
American Association of Pathologists |
| 1993 |
Nomination Committee, American Association of Immunologists |
| 1995- |
Society for Leukocyte Biology |
| 1996- |
National Academy of Sciences |
| 2001 |
Canadian Vaccines and Immunotherapeutics Network, Scientific Advisor |
| 2004-2007 |
Chair of Section 29, Biophysics and Computational Biology, National Academy of Sciences |
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Consulting: |
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| 1989-1995 |
Boehringer-Ingelheim
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| 1992-1999 |
LeukoSite, Inc., Founder and Chairman of Scientific Advisory Board
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| 1997- |
Molecular Applications Group, Inc., Scientific Advisory Board
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| 1999-2001 |
Millennium Pharmaceuticals |
| 2003- |
Sunesis Pharmaceuticals |
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Teaching Experience:
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| 1972-1974 |
Harvard University, Biochemistry 10 Teaching Assistant |
| 1974-1975 |
Harvard University, Biochemistry 111 Teaching Assistant |
| 1981 |
Instructor, Alton Jones Cell Culture Center Course on Macrophages, Lake Placid, NY |
| 1984, 1986 |
Developed and led Harvard Medical School Continuing Education Course, "Hybridomas in Biotechnology and Medicine" |
| 1985- |
Course leader and lecturer, Harvard University, Immunology 203, "Biochemistry and Molecular Biology of the Immune System" |
| 1988- |
Lecturer, "Identity, Microbes and Defense," in New Pathway Curriculum |
| 1989 |
Lecturer, Human Pathology, HST-030
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| 1988- |
Lecturer, Cell Biology 200a "Molecular Development of the Cell"
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| 1993 |
Lecturer, Human Pathology, HST-030
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| 1994 |
Course leader and lecturer, Harvard University, Immunology 203,
"Biochemistry and Molecular Biology of the Immune System" |
| 1994 |
Lecturer, Human Pathology, HST-030
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| 1995 |
Lecturer, Human Pathology, HST-030
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| 1995 |
Lecturer, Harvard Medical School Immunology Seminar
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| 1995 |
Lecturer, Harvard University Department of Molecular and Cellular Biology Seminar Series |
| 1996 |
Lecturer, Human Pathology, HST-030
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| 1996 |
Lecturer, Harvard Medical School Immunology Seminar
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| 1997 |
Lecturer, Harvard Medical School Pathology Seminar
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| 1997 |
Lecturer, Human Pathology, HST-030
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| 1998 |
Lecturer, Human Pathology, HST-030
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| 1998 |
Lecturer, Harvard University, Advanced Biomedical Sciences Course "Revisiting Biomedical Sciences and Pathology"
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| 1999 |
Lecturer, Harvard University, Molecular and Cellular Immunology 169 |
| 1999 |
Presentation to Graduate Students, Harvard University, Biological and Biomedical Sciences |
| 1999, 2001 |
Lecturer, Harvard University, Molecular Immunology 268 |
| 2003 |
Lecturer, Harvard University, Immunology Critical Reading Course 204 |
| 2007 |
Lecturer, Harvard University, Department of Biological Chemistry and Molecular Pharmacology 201 Proteins |
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Selected Lectures and Honors:
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| 1990 |
Visiting Professor, University of Michigan
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| 1991 |
Centennial Celebration-Scientific Symposium, Washington University School of Medicine |
| 1991 |
Harvey Lecturer, William Harvey Research Institute, St. Bartholomew's, London, England |
| 1992 |
Keynote Address, joint Keystone Symposia on "Inflammation, Growth Regulatory Molecules, and Atherosclerosis", and "The Molecular Biology of the Endothelial Cell" |
| 1992 |
Ninth Zoltan Ovari Symposium Lecturer, The Honors Program, New York University Medical Center |
| 1992 |
First Annual Invited Speaker, Pathology Department, Albert Einstein School of Medicine |
| 1992 |
14th Annual Jim McGinnis Memorial Lecturer, Duke University Medical Center |
| 1992 |
Lecturer, National Heart, Lung and Blood Institute Symposium on Atherosclerosis to Honor Gardner McMillian, Bethesda, Maryland |
| 1992 |
Boehringer-Ingelheim Distinguished Lecturer in Biomedical Sciences, Vanderbilt University |
| 1993 |
Lecturer, William B. Coley Symposium, Frontiers of Immunology and Cancer Immunology, Cancer Research Institute and Memorial Sloan-Kettering, New York, New York |
| 1994 |
Lecturer, The Harvey Society, New York, New York |
| 1994 |
Juan March Foundation Lecturer, Madrid, Spain |
| 1994 |
Basic Science Lecturer, The American Association for Thoracic Surgery Annual Meeting, New York, New York |
| 1994 |
Burroughs-Wellcome Visiting Professor, Royal Society of Medicine, London, Cambridge, Birmingham, and Oxford, England |
| 1994 |
Second Annual Norman Heatley Lecturer, University of Oxford, Sir William Dunn School of Pathology, Oxford, England |
| 1995 |
Second Daiichi Lecturer, University of California, San Francisco, "The effect of force on bond lifetimes :Are selectins and integrins specialized for high tensile strength?" |
| 1995 |
Lecturer, Nobel Conference on "Cell Adhesion Molecules and Cell-Matrix Receptors in Vertebrate Tissues", Karolinska Institutet, Stockholm, Sweden |
| 1995 |
Plenary Speaker and Symposium Co-Chair on Selectins, World Congress on Inflammation, Brighton, England |
| 1996 |
Plenary Lecturer, Keystone Symposium, Exploring and Exploiting Antibody and Ig Superfamily Combining Sites, Taos, New Mexico |
| 1996 |
Co-Organizer and Speaker, Vascular Endothelium and Regulation of Leukocyte Traffic Meeting, Instituto Juan March de Estudios e Investigaciones, Madrid, Spain |
| 1997 |
Wellcome Visiting Professor, Wayne State University, Detroit, Michigan |
| 1998 |
Presidential Symposium Speaker on Integrin Receptors, American Society of Haematology, Miami, Florida. |
| 1998 |
Keynote Lecturer, Third International Workshop on Signal Transduction in the Activation and Development of Mast Cells and Basophils, The National Institute of Health, Bethesda, Maryland. |
| 1999 |
John T. Edsall Lecturer, Department of Molecular and Cellular Biology, Harvard University, Cambridge, Massachusetts |
- 2000
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George W. Raiziss Biochemical Rounds Seminar Series, "Molecular Interactions in Biology and Medicine", University of Pennsylvania School of Medicine, Philadelphia |
| 2001 |
Keynote Address, Keystone Symposium, “Chemokine and Chemokine Receptors”, Taos, New Mexico |
| 2001 |
Keynote Speaker, NCI Center for Cancer Research, Fellows Symposium, Bethesda, Maryland |
| 2003 |
Speaker, The Future of Structural Biology, New York Structural Biology Center, New York, New York |
| 2003 |
Speaker, Dean's Lecture at Mount Sinai School of Medicine, New York, New York |
| 2004 |
Speaker, President's Research Seminar Series, Memorial Sloan-Kettering Cancer Center, New York, New York |
| 2006 |
12th Annual Edmond Alexandre Goidl Lectureship, on Immunology University of Maryland at Baltimore, School of Medicine, Baltimore, Maryland |
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